Abdominal Pain Location Guide

Pain Location and Possible Causes
Epigastric Pain
- Reflux, gastritis, peptic ulcer disease, pancreatitis, atypical MI, AAAā
Left Upper Quadrant Pain
- Splenic pathology, gastritis, pancreatitis
Left Iliac Fossa Pain
- Diverticulitis, ulcerative colitis, gynaecological pathology
Suprapubic Pain
- UTI, urinary retention, pelvic inflammatory disease, pregnancy-related causes, testicular torsion
Right Upper Quadrant Pain
- Gallstones, cholecystitis, cholangitis, hepatitis
Right Iliac Fossa Pain
- Appendicitis, Crohnās disease, gynaecological pathology
Flank Pain
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renal colic, pyelonephritis, AAA
Appendicitis
Classically presents with central abdominal pain that migrates to the right iliac fossa.
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Associated symptoms may include:
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Anorexia
Nausea
Vomiting
Fever
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Biliary Colic, Cholecystitis & Cholangitis
Usually causes right upper quadrant or epigastric pain
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Features may include:
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Pain after fatty foods
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Radiation to the right shoulder tip
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Nausea or vomiting
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Fever if cholecystitis or cholangitis is present
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Jaundice with cholangitis
Peptic Ulcer Disease
Usually causes epigastric burning pain.
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Features may include:
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Relation to meals
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NSAID use
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Smoking and alcohol
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Haematemesis
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Melaena
Pancreatitis
Epigastric pain radiating to the back. Consider this in alcohol users and patients with Gallstones.
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Ask about:
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Nausea and vomiting
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Fever
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Palpitations and Tachycardia
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Abdominal and Swelling
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Hydration/Volume Status
Gastroenteritis
Often causes crampy abdominal pain with vomiting and diarrhoea.
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Ask about:
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Sick contacts
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Recent food exposure
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Recent travel
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Fever
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Blood in stool
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Hydration/volume status
Inflammatory Bowel Disease
This encompasses Crohns and Ulcerative Colitis. These may cause pain throughout the abdomen.
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Ask about:
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Passing mucous or blood rectally
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Abnormal bowel habit, frequency passing stools
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Anaemia symptoms (tiredness)
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Poor appetitie, weight loss
Renal Colic
Often causes flank pain radiating to the groin.
Ask about:
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Waves of severe pain
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Haematuria
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Nausea or vomiting
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Urinary symptoms
Pyelonephritis
Can present similar to UTI/Colic with flank pain or suprapubic pain.
Ask about:
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Urinary tract symptoms: dysuria/haematuria
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Fever
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Loin to groin pain
Diverticulitis
Typically causing left illiac fossa pain.
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Ask about:
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Blood in the stool
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Altered bowel habit
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Abdominal bloating
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Fever
OSCE Talk Tip
Abdominal Aortic Aneurysm and Aortic Dissection can present with generalised abdominal pain and an unwell patient. This is one to always consider, especially in older patients with risk factors (hypertension, smoking, male, connective tissue disorders, >65)

Urinary Tract Infection
Suprapubic pain. Consider this in elderly patients off baseline/with delirium.
Ask about:
Urinary tract symptoms: dysuria/haematuria/foul smelling urine/frequency
Sexual history and safe sex
Multiple recent UTIs (consider diabetes or structural renal pathology)
Are they passing urine? If not consider retention and urgent catheterisation
Testicular Torsion
Suprapubic pain can be present, alongside severe groin/testicular pain.
Needs urological and surgical input urgently.
Ask about:
Swelling/erythema of the scrotum
Nausea/vomiting
Pain worse with moving/walking


Gynaecological Pathology
This includes torsion, cysts, PID, endometriosis, and ectopic pregnancy
This may cause pain anywhere in the abdomen and can be under investigated.
Ask about:
Menstrual cycle, irregularity, pain, heavy periods
Pregnancy
Sexually transmitted infections
Nausea/vomiting
Temperatures